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Gene therapy injection into spinal cord halts ALS in adult mice

Animal studies have already suggested that ALS can be prevented by replacing the mutated genes that cause some forms of the condition with normal versions. But delivering genes to nerve cells in the spine is a challenge.

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Brain scans from dozens of mice may reveal autism subtypes

Analyzing large numbers of autism mice, researchers have found that the mice cluster into subtypes based on brain structure and functional connectivity.

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A cure for cancer: how to kill a killer

Revolutionary work on the body’s immune system and a host of new drug trials mean that beating cancer may be achievable

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How Are Dogs Helping Us Cure Cancer in People?

The field of comparative oncology leverages other mammals’ cancers to develop better human treatments.

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A selfish gene makes mice into migrants

House mice carrying a specific selfish supergene move from one population to another much more frequently than their peers.

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Scientists develop novel vaccine for Lassa fever and rabies

A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications.

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Mouse study reveals more clues in link between normal breast changes and invasive breast cancer

Before this study, investigators did not know how autophagy is in play during involution and how it is different in the reversible versus irreversible phase of involution.

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Changes in mitochondrial DNA control how nuclear DNA mutations are expressed in cardiomyopathy

Greater understanding of these genetic interactions may eventually permit improved diagnostics and therapies for patients with cardiomyopathy

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